USA take on Colombia in the opening match of the Copa América Centenario at what will be a star-studded party as the world's oldest international football tournament gets under way in Santa Clara California on Friday at the Levi's Stadium.
The best football teams from across the Americas
Sixteen teams from across the Americas have gathered in the United States for this special one-off edition of the Copa América, which is being staged to mark the tournament's 100th anniversary.
Messi, Suárez, James among the stars
Argentina's Lionel Messi, Uruguay's Luis Suarez and Colombia's James Rodriguez are among the stars due to be in action throughout the tournament, which runs from June 3 to 26.
Excitement at the event appears to now be running high, despite a troubled build-up dogged by corruption allegations that threatened to derail the event.
Biggest tournament in the USA since the 1994 World Cup
Ten teams from South America are joined by six teams from the North America, Central America and Caribbean region (CONCACAF), in what is arguably the biggest tournament to be staged on US soil since the 1994 World Cup.
The tournament is being seen in some quarters as a statement of intent for a bid for the 2026 World Cup, which US officials have signaled they intend to bid for as football in the United States steadily grows in popularity.
Levi's Stadium in Santa Clara
The gleaming Levi's Stadium in Santa Clara -- home of the San Francisco 49ers and the venue for this year's Super Bowl -- is expected to be close to its 68,500 capacity on Friday for the USA's Group A opener against Colombia.
Whether spectator demand for other matches will be as high is doubtful; few are expecting matches involving the tournament minnows to be sell-outs.
In comments to Sports Illustrated, United States Soccer Federation chief Sunil Gulati said he expected the tournament to meet its targets.
"It's a big event, and I think our goals will be met by the time the event is over in terms of attendance and interest," Gulati said.
"There's a lot of star power, and we open with a great game with the US and Colombia."
Most teams have full-strength squads
Most teams have chosen full-strength squads, although injuries and the proximity of the Olympics have deprived Brazil of several first choice players including Barcelona superstar Neymar.
"Everyone has brought the best players who are available to them and they're taking it seriously. That's a plus," said Gulati.
Copa América: a logistical triumph
That the tournament is taking place at all is something of a logistical triumph.
Although first announced in 2014, the fate of the event hung in the balance for much of 2015 after the arrest and indictment of several of the officials from South America and CONCACAF responsible for dreaming up the tournament.
When plans for the tournament were launched at a glitzy event in Miami two years ago, CONCACAF President Jeffrey Webb stood proudly alongside South American federation (CONMEBOL) chief Eugenio Figueredo.
But Webb and Figueredo were among several officials arrested in Switzerland in May last year as part of the US-led corruption investigation that ultimately led to the sensational downfall of FIFA President Sepp Blatter.
With impeccable timing, Webb is due to appear in a New York courtroom on Friday -- the day of the tournament's opening match -- to face sentencing for his role in the scandal.
Figueredo, 84, was extradited to Uruguay from Switzerland last December and also faces criminal prosecution.
Both Figueredo and Webb -- as well as former CONMEBOL chief Nicolas Leoz -- are accused of pocketing millions of dollars in bribes linked to the award of media rights for the tournament, part of a scam dubbed a "World Cup of Fraud" by US prosecutors.
Organizers will hope that the sleazy background will be forgotten once the action finally gets under way.
Argentina aiming to put title drought to an end
Messi and Argentina will be aiming to win the country's first major title since the 1993 Copa America after a series of recent near-misses.
Messi, who was late to join the Argentina squad after appearing at his tax fraud trial in Spain on Thursday, is a doubt for Argentina's opening game against Chile in in Santa Clara next Monday. Panama and Bolivia complete Group D.
Hosts start against Colombia
The United States meanwhile aim to get off to a winning start against Colombia on Friday as they seek to navigate a difficult group which also includes Costa Rica and Paraguay.
Five-time World Cup winners Brazil will be favored to emerge from Group B, where they face Ecuador, Haiti and Peru.
The Brazilians open against Ecuador at Pasadena's Rose Bowl on Saturday -- scene of their victory at the 1994 World Cup final.
Mexico and Uruguay will be expected to progress from Group C, with Jamaica and Venezuela completing the field.