Las Palmas welcome Barcelona to the Canary Islands with the away side eager to keep the pressure on Real Madrid as the La Liga title race enters the final straight.
Quique Setién's side have been in a poor run of form since the coach announced that he will leave at the end of the season. Barça, by contrast, have recorded five consecutive victories to ensure that as they say in Spain: 'hay liga', there is a title race.
Kevin Prince Boateng returns from suspension for Las Palmas, as is PSG loanee Jesé. The latter, formerly of Real Madrid, is keen to de-rail Barça's title challenge.
Lopes will deputise for the absent Castellano at left back.
Roque Mesa will pull the strings in the centre of the park, along with Momo and Montero.
Las Palmas XI: Varas; Macedo, Lemos, Bigas, Lopes; Montoro, Momo, Mesa; Viera, Boateng, Jesé.
Coach: Quique Setién
Gerard Piqué's illness and Sergi Roberto's suspension leaves Barça light in defence.
Digne and Alba are both in the line-up, with the former expected to start at centre-half.
In midfield and attack, Barcelona line up as expected.
Barcelona XI: Ter Stegen; Mascherano, Umtiti, Digne, Alba; Rakitic, Iniesta, Busquets; Neymar, Suárez, Messi.
Coach: Luis Enrique