Sergio Busquets has a bout of gastroenteritis and misses tonight's match between Spain and Switzerland, with kick-off at 21:00 at La Cerámica in Villarreal.
Lopetegui as expected has gone with Diego Costa and Iago Aspas up front.
Spain starting XI
De Gea; Odriozola, Piqué, Azpilicueta, Jordi Alba; Koke, Thiago, Iniesta; Silva, Iago Aspa and Diego Costa.
Switzerland starting XI
Sommer, Rodríguez, Akanji, Schar, Lichtsteiner, Zakaria, Behrami, Zuber, Dzemaili, Shaqiri and Seferovic.