New scientific study reveals a common sweetener could have unexpected effects on the brain

Erythritol is a widely used sweetener in low-calorie drinks and foods. However, a study from the University of Colorado warns of a link between high erythritol levels and an increased risk of cardiovascular and cerebrovascular events.

It is primarily used because it sweetens foods without significantly raising blood sugar levels, making it popular in low-carb products and among people trying to reduce their sugar intake.

What does the report reveal?

The study found that erythritol may affect both heart and brain health. High levels of this sweetener increase stress on the cells that line blood vessels, specifically cerebral microvascular endothelial cells, which help regulate blood flow and ensure the brain receives oxygen and nutrients. It reduces substances such as nitric oxide, which help blood vessels relax, and increases others such as endothelin-1, which cause vessels to constrict.

The researchers did not study erythritol in people but instead examined human cells in a laboratory setting. According to the report, they exposed the cells to different concentrations similar to those that might be found in the blood of someone who consumes beverages or snacks containing this sweetener. They then compared them with cells that were not exposed to observe the differences.

The findings reinforce what other studies have previously suggested: a link between erythritol consumption and higher rates of heart attacks and strokes.

Healthy blood vessels function like traffic controllers, widening when organs need more blood, such as during exercise, and tightening when less is required. This balance is made possible by two molecules, nitric oxide and endothelin-1. According to the researchers, erythritol disrupts this system. This imbalance is a warning sign of an ischemic stroke, which is caused by blood clots.

In fact, the study explains that erythritol may undermine the body’s natural defense against clots. Normally, when clots form in blood vessels, cells release tissue plasminogen activator, or t-PA, which dissolves the blockage before it can cause a stroke.

The researchers emphasize the need for further studies, particularly in animals and humans, to confirm these findings and better understand the potential health effects. They caution that the current evidence is limited to laboratory experiments and recommend moderation in the frequent consumption of non-nutritive sweeteners until their effects are better understood.

Get your game on! Whether you’re into NFL touchdowns, NBA buzzer-beaters, world-class soccer goals, or MLB home runs, our app has it all.

Dive into live coverage, expert insights, breaking news, exclusive videos, and more – plus, stay updated on the latest in current affairs and entertainment. Download now for all-access coverage, right at your fingertips – anytime, anywhere.