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NFL

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NFL week 1 complete odds and predictions

NFL is back Thursday with an exciting matchup between the Bills and the reigning Super Bowl champs, the Rams. Check out the odds for each Week 1 game.

Jennifer Bubel
Jennifer BubelEnglish_AS
We’re just 10 days away from the start of the 2022-23 season that kicks off when the Buffalo Bills take on the Super Bowl champions, Los Angeles Rams.

Football is back, baby! The NFL couldn’t be kicking off with a more exciting matchup to start the season. The Buffalo Bills will take on the Los Angeles Rams at SoFi Stadium, the Rams’ home field and where they won it all just last February. The Bills are favorited by many to win this year’s Super Bowl. Could we be looking at a preview for Super Bowl 2023? There are plenty of other exciting games to look forward to this week as the NFL gets back into action.

Related: NFL Week 1 Preview

Let’s take a look at the odds for each game and the predicted winners.

NFL week 1 complete odds and predictions

Buffalo Bills at Los Angeles Rams

Thursday, September 8 - 8:20 p.m. ET at SoFi Stadium

The Bills are favorites to win and the Rams are the underdogs.

  • Tipico Sportsbook: Bills -2.5 (-112) Rams +2.5 (-108)
  • Draft Kings Sportsbook: Bills -2.5 (-110) Rams +2.5 (-110)
  • Ceasars Sportsbook: Bills -2.5 (-110) Rams +2.5 (-110)
  • Fanduel Sportsbook: Bills -2.5 (-106) Rams +2.5 (-114)
  • Bet MGM: Bills -2.5 (-110) Rams +2.5 (-110)
  • Points Bet: Bills -2.5 (-110) Rams +2.5 (-110)
  • Bet Rivers: Bills -2.5 (-110) Rams +2.5 (-110)
  • Unibet: Bills -2.5 (-110) Rams +2.5 (-110)

Philadelphia Eagles at Detroit Lions

Sunday, September 11 - 1 p.m. ET at Ford Field

The Eagles are favorites to win and the Lions are the underdogs.

  • Tipico Sportsbook: Eagles -3.5 (-115) Lions +3.5 (-105)
  • Draft Kings Sportsbook: Eagles -4 (-110) Lions +4 (-110)
  • Ceasars Sportsbook: Eagles -4 (-110) Lions +4 (-110)
  • Fanduel Sportsbook: Eagles -3.5 (-114) Lions +3.5 (-106)
  • Bet MGM: Eagles -4 (-110) Lions +4 (-110)
  • Points Bet: Eagles -4 (-105) Lions +4 (-105)
  • Bet Rivers: Eagles -4 (-108) Lions +4 (-113)
  • Unibet: Eagles -4 (-108) Lions +4 (-113)

New Orleans Saints at Atlanta Falcons

Sunday, September 11 - 1 p.m. ET at Mercedez Benz Stadium

The Saints are favorites to win and the Falcons are the underdogs.

  • Tipico Sportsbook: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Draft Kings Sportsbook: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Ceasars Sportsbook: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Fanduel Sportsbook: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Bet MGM: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Points Bet: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Bet Rivers: Saints -5.5 (-110) Falcons +5.5 (-110)
  • Unibet: Saints -5.5 (-110) Falcons +5.5 (-110)

Cleveland Browns at Carolina Panthers

Sunday, September 11 - 1 p.m. ET at Bank of America Stadium

The Panthers are favorites to win and the Browns are the underdogs.

  • Tipico Sportsbook: Browns +2.5 (-105) Panthers -2.5 (-115)
  • Draft Kings Sportsbook: Browns +2.5 (-110) Panthers -2.5 (-110)
  • Ceasars Sportsbook: Browns +2.5 (-110) Panthers -2.5 (-110)
  • Fanduel Sportsbook: Browns +2.5 (-108) Panthers -2.5 (-112)
  • Bet MGM: Browns +2.5 (-110) Panthers -2.5 (-110)
  • Points Bet: Browns +2.5 (-110) Panthers -2.5 (-110)
  • Bet Rivers: Browns +2.5 (-110) Panthers -2.5 (-110)
  • Unibet: Browns +2.5 (-110) Panthers -2.5 (-110)

San Francisco 49ers at Chicago Bears

Sunday, September 11 - 1 p.m. ET at Soldier Field

The 49ers are favorites to win and the Bears are the underdogs.

  • Tipico Sportsbook: 49ers -6.5 (-125) Bears +6.5 (+102)
  • Draft Kings Sportsbook: 49ers -7 (-105) Bears +7 (+115)
  • Ceasars Sportsbook: 49ers -7 (-110) Bears +7 (+110)
  • Fanduel Sportsbook: 49ers -6.5 (-12o) Bears +6.5 (+102)
  • Bet MGM: 49ers -7 (-110) Bears +7 (+110)
  • Points Bet: 49ers -6.5 (-115) Bears +6.5 (+105)
  • Bet Rivers: 49ers -7 (-110) Bears +7 (+110)
  • Unibet: 49ers -7 (-110) Bears +7 (+110)

Pittsburgh Steelers at Cincinnati Bengals

Sunday, September 11 - 1 p.m. ET at Paycor Stadium

The Bengals are favorites to win and the Steelers are the underdogs.

  • Tipico Sportsbook: Steelers +6.5 (-112) Bengals -6.5 (-108)
  • Draft Kings Sportsbook: Steelers +6.5 (-110) Bengals -6.5 (-110)
  • Ceasars Sportsbook: Steelers +6.5 (-110) Bengals -6.5 (-110)
  • Fanduel Sportsbook: Steelers +6.5 (-115) Bengals -6.5 (-105)
  • Bet MGM: Steelers +6.5 (-110) Bengals -6.5 (-110)
  • Points Bet: Steelers +6.5 (-110) Bengals -6.5 (-110)
  • Bet Rivers: Steelers +6.5 (-110) Bengals -6.5 (-110)
  • Unibet: Steelers +6.5 (-110) Bengals -6.5 (-110)

Indianapolis Colts at Houston Texans

Sunday, September 11 - 1 p.m. ET at NRG Stadium

The Colts are favorites to win and the Texans are the underdogs.

  • Tipico Sportsbook: Colts -7.5 (-115) Texans +7.5 (-105)
  • Draft Kings Sportsbook: Colts -8 (-115) Texans +8 (-105)
  • Ceasars Sportsbook: Colts -8 (-110) Texans +8 (-110)
  • Fanduel Sportsbook: Colts -8 (-115) Texans +8 (-105)
  • Bet MGM: Colts -8 (-110) Texans +8 (-110)
  • Points Bet: Colts -8 (-110) Texans +8 (-110)
  • Bet Rivers: Colts -8 (-112) Texans +8 (-109)
  • Unibet: Colts -8 (-112) Texans +8 (-109)

New England Patriots at Miami Dolphins

Sunday, September 11 - 1 p.m. ET at Hard Rock Stadium

The Dolphins are favorites to win and the Patriots are the underdogs.

  • Tipico Sportsbook: Patriots +3.5 (-125) Dolphins -3.5 (+102)
  • Draft Kings Sportsbook: Patriots +3 (-110) Dolphins -3 (+110)
  • Ceasars Sportsbook: Patriots +3 (-110) Dolphins -3 (+110)
  • Fanduel Sportsbook: Patriots +2.5 (-104) Dolphins -2.5 (+128)
  • Bet MGM: Patriots +3 (-110) Dolphins -3 (+110)
  • Points Bet: Patriots +3 (-110) Dolphins -3 (+110)
  • Bet Rivers: Patriots +3 (-110) Dolphins -3 (+110)
  • Unibet: Patriots +3 (-110) Dolphins -3 (+110)

Baltimore Ravens at New YorkJets

Sunday, September 11 - 1 p.m. ET at MetLife Stadium

The Ravens are favorites to win and the Jets are the underdogs.

  • Tipico Sportsbook: Ravens -6.5 (-120) Jets +6.5 (+100)
  • Draft Kings Sportsbook: Ravens -7 (-105) Jets +7 (+115)
  • Ceasars Sportsbook: Ravens -7 (-105) Jets +7 (+115)
  • Fanduel Sportsbook: Ravens -6.5 (-114) Jets +6.5 (+106)
  • Bet MGM: Ravens -7 (-105) Jets +7 (+115)
  • Points Bet: Ravens -7 (-110) Jets +7 (+110)
  • Bet Rivers: Ravens -7 (-108) Jets +7 (+110)
  • Unibet: Ravens -7 (-108) Jets +7 (+110)

Jacksonville Jaguars at Washington Commanders

Sunday, September 11 - 1 p.m. ET at FedEx Field

The Commanders are the favorites to win and the Jaguars are the underdogs.

  • Tipico Sportsbook: Jaguars +3.5 (-130) Commanders -3.5 (+105)
  • Draft Kings Sportsbook: Jaguars +3 (-105) Commanders -3 (+115)
  • Ceasars Sportsbook: Jaguars +3 (-110) Commanders -3 (+110)
  • Fanduel Sportsbook: Jaguars +3.5 (-120) Commanders -3.5 (+102)
  • Bet MGM: Jaguars +3 (-110) Commanders -3 (+110)
  • Points Bet: Jaguars +3 (-105) Commanders -3 (+115)
  • Bet Rivers: Jaguars +3 (-110) Commanders -3 (+110)
  • Unibet: Jaguars +3 (-110) Commanders -3 (+110)

New York Giants at Tennessee Titans

Sunday, September 11 - 4:25 p.m. ET at Nissan Stadium

The Titans are the favorites and the Giants are the underdogs.

  • Tipico Sportsbook: Giants +5.5 (-110) Titans -5.5 (-110)
  • Draft Kings Sportsbook: Giants +5.5 (-110) Titans -5.5 (-110)
  • Ceasars Sportsbook: Giants +5.5 (-110) Titans -5.5 (-110)
  • Fanduel Sportsbook: Giants +5.5 (-110) Titans -5.5 (-110)
  • Bet MGM: Giants +6 (-110) Titans -6 (-110)
  • Points Bet: Giants +5.5 (-115) Titans -5.5 (-105)
  • Bet Rivers: Giants +5.5 (-110) Titans -5.5 (-110)
  • Unibet: Giants +5.5 (-110) Titans -5.5 (-110)

Kansas City Chiefs at Arizona Cardinals

Sunday, September 11 - 4:25 p.m. ET at State Far, Stadium

The Chiefs are favorites to win and the Cardinals are underdogs.

  • Tipico Sportsbook: Chiefs -4.5 (-105) Cardinals +4.5 (-115)
  • Draft Kings Sportsbook: Chiefs -4.5 (-110) Cardinals +4.5 (-110)
  • Ceasars Sportsbook: Chiefs -4.5 (-110) Cardinals +4.5 (-110)
  • Fanduel Sportsbook: Chiefs -3.5 (-115) Cardinals +3.5 (-105)
  • Bet MGM: Chiefs -4.5 (-110) Cardinals +4.5 (-110)
  • Points Bet: Chiefs -4.5 (-110) Cardinals +4.5 (-110)
  • Bet Rivers: Chiefs -4.5 (-105) Cardinals +4.5 (-115)
  • Unibet: Chiefs -4.5 (-105) Cardinals +4.5 (-115)

Las Vegas Raiders at Los Angeles Chargers

Sunday, September 11 - 4:25 p.m. ET at SoFi Stadium

The Chargers are the favorites to win and the Raiders are the underdogs.

  • Tipico Sportsbook: Raiders +3.5 (-112) Chargers -3.5 (-108)
  • Draft Kings Sportsbook: Raiders +3.5 (-110) Chargers -3.5 (-110)
  • Ceasars Sportsbook: Raiders +3.5 (-100) Chargers -3.5 (-120)
  • Fanduel Sportsbook: Raiders +3.5 (-118) Chargers -3.5 (-104)
  • Bet MGM: Raiders +3.5 (-110) Chargers -3.5 (-110)
  • Points Bet: Raiders +3.5 (-110) Chargers -3.5 (-110)
  • Bet Rivers: Raiders +3.5 (-115) Chargers -3.5 (-105)
  • Unibet: Raiders +3.5 (-115) Chargers -3.5 (-105)

Green Bay Packers at Minnesota Vikings

Sunday, September 11 - 4:25 p.m. ET at U.S. Bank Stadium

The Packers are the favorites to win and the Vikings are the underdogs.

  • Tipico Sportsbook: Packers -1.5 (-115) Vikings +1.5 (-105)
  • Draft Kings Sportsbook: Packers -1.5 (-110) Vikings +1.5 (-110)
  • Ceasars Sportsbook: Packers -1.5 (-110) Vikings +1.5 (-110)
  • Fanduel Sportsbook: Packers -1.5 (-105) Vikings +1.5 (-115)
  • Bet MGM: Packers -1.5 (-110) Vikings +1.5 (-110)
  • Points Bet: Packers -1.5 (-105) Vikings +1.5 (-115)
  • Bet Rivers: Packers -1.5 (-110) Vikings +1.5 (-110)
  • Unibet: Packers -1.5 (-110) Vikings +1.5 (-110)

Tampa Bay Buccaneers at Dallas Cowboys

Sunday, September 11 - 8 p.m. ET at AT&T Stadium

The Buccaneers are the favorites to win and the Cowboys are the underdogs.

  • Tipico Sportsbook: Buccaneers -1.5 (-112) Cowboys +1.5 (-108)
  • Draft Kings Sportsbook: Buccaneers -1.5 (-110) Cowboys +1.5 (-110)
  • Ceasars Sportsbook: Buccaneers -1.5 (-110) Cowboys +1.5 (-110)
  • Fanduel Sportsbook: Buccaneers -1.5 (-114) Cowboys +1.5 (-106)
  • Bet MGM: Buccaneers -1.5 (-110) Cowboys +1.5 (-110)
  • Points Bet: Buccaneers -1.5 (-105) Cowboys +1.5 (-115)
  • Bet Rivers: Buccaneers -1.5 (-110) Cowboys +1.5 (-110)
  • Unibet: Buccaneers -1.5 (-110) Cowboys +1.5 (-110)

Denver Broncos at Seattle Seahawks

Monday, September 12 - 8:15 p.m. ET at Lumen Field

The Broncos are the favorites to win and the Seahawks are the underdogs.

  • Tipico Sportsbook: Broncos -6.5 (-105) Seahawks +6.5 (-115)
  • Draft Kings Sportsbook: Broncos -6.5 (-110) Seahawks +6.5 (-110)
  • Ceasars Sportsbook: Broncos -6.5 (-110) Seahawks +6.5 (-110)
  • Fanduel Sportsbook: Broncos -6.5 (-106) Seahawks +6.5 (-114)
  • Bet MGM: Broncos -6.5 (-110) Seahawks +6.5 (-110)
  • Points Bet: Broncos -6.5 (-105) Seahawks +6.5 (-115)
  • Bet Rivers: Broncos -6.5 (-109) Seahawks +6.5 (-112)
  • Unibet: Broncos -6.5 (-109) Seahawks +6.5 (-112)