Rams vs. 49ers: Bets and predictions for Monday Night Football
The San Francisco 49ers have won the last six regular season games against the Rams.
Tonight Monday Night Football is back for the last game of Week 4. Last year’s Super Bowl winners Los Angeles Rams, visit the San Francisco 49ers in a matchup for the NFC West Division.
After losing 31-10 to Buffalo at home in their first game of the 2022 NFL season, the Rams have won their next two games: 31-27 at Atlanta and 20-12 at Arizona last week.
The 49ers arrive with a 1-2 record, and in both losses, they have only been able to score 10 points: 19-10 against Chicago and 11-10 against Denver. Their only win came in Week 2, 27-7, over the Seattle Seahawks.
Rams vs. 49ers odds
Spread: 49ers by 2
Over/under: 42.5
Moneyline: Rams +105, 49ers -125
What you should know
The 49ers have won the last six regular-season games (the Rams won last season’s NFC Championship Game).
San Francisco head coach Kyle Shanahan is 7-4 against the Rams’. Sean McVay is 29-13 in road games in the regular season.
Rams wide receiver Cooper Kupp had at least 11 receptions and 120 yards in his three most recent appearances on Monday Night Football.
San Francisco is the 28th team since the 2000 season to allow 28 points or fewer in the first three games and the only team with a losing record.
The 49ers have turned over five balls in their two losses and none in their only win.
San Francisco’s defense has allowed 3.94 yards per play, the lowest in the NFL.
injuries
Rams
Safety Derion Kendrick started the week in concussion protocol.
Defensive backs Cobie Durant (hamstring), David Long (groin), and Jordan Fuller (hamstring) missed last week’s game and are in doubt for the MNF.
On Monday, they activated tackle Chandler Brewer and running back Malcolm Brown from the practice squad.
49ers
Left tackle Trent Williams suffered a sprained ankle last week and will likely be replaced by Colton McKivitz.
This Monday, they announced that wide receiver Willie Snead IV was elevated from the practice squad to the active roster. To make room for him on the roster, the team placed linebacker Azeez Al-Shaair (knee) on injured reserve.
Running back Tevin Coleman and wide receiver Malik Turner were also promoted from the practice squad.
Defensive tackle Arik Armstead (foot) is expected to return tonight.
Key duel
CB Jalen Ramsey vs. W.R. Deebo Samuel
Ramsey is considered by many to be the best cornerback in the NFL. Still, in the Rams’ most recent visit to San Francisco (Week 10 of the 2021 campaign, also on MNF), Samuel had five receptions, 97 yards, and a 40-yard touchdown courtesy of Jimmy Garoppolo; In addition, he carried the ball on the ground five times for another 36 yards and a touchdown.
Prediction
San Francisco is second to last in points scored per game (15.7), but leads in points allowed (12.3). However, we can’t ignore the 49ers’ winning streak over the Rams, so the pick is San Francisco 23-20 LA Rams.