Players Games played as substitute

Pos.	Player	Team	Total
1	Adrien Perez Forward	Los Angeles FC	2Games played as substitute
	Escoboza Forward	América	2
	Leonardo Ramos Forward	León FC	2
	Maidana Midfielder	Olimpia de Tegucigalpa	2
	Adam Jahn Forward	Atlanta United FC	2
	Julián Quiñones Forward	Tigres	2
	Jown Cardona Midfielder	León FC	2
	Valentín Castellano Midfielder	New York City	2
	Maxi Moralez Midfielder	New York City	2
	Anthony Jackson-Hamel Forward	Montreal Impact	2
	Jonathan Martínez Midfielder	Saprissa	2
	Wálter Martínez Forward	Motagua	2
	Ballou Jean-Yves Tabla Midfielder	Montreal Impact	2
	Ariel Rodríguez Forward	Saprissa	2
	Román Martínez Forward	América	2
	Jorge Benguche Forward	Olimpia de Tegucigalpa	2
	Gonzalo Klusener Forward	Motagua	2
	José Varela Midfielder	Alianza San Salvador	2
	Joel Waterman Defender	Montreal Impact	2
	Maximiliano Lombardi Midfielder	Comunicaciones	2
2	Roberto Alvarado Midfielder	Cruz Azul	1
	Maximiliano Freitas Forward	Alianza San Salvador	1
	Taider Midfielder	Montreal Impact	1
	Yoshimar Yotún Midfielder	Cruz Azul	1
	Francisco Córdova Midfielder	América	1
	Vargas Forward	Tigres	1
	Francisco Ginella Midfielder	Los Angeles FC	1
	Ismael Tajouri Midfielder	New York City	1
	Diego Barraza Defender	Cruz Azul	1
	José Cañete Defender	Olimpia de Tegucigalpa	1
	Mohammed Adams Midfielder	Atlanta United FC	1
	Federico Viñas Forward	América	1
	Shane O'Neill Defender	Seattle Sounders	1
	Luis Castro Midfielder	Atlanta United FC	1
	Luiz Fernando Midfielder	Atlanta United FC	1
	Justin Dhillon Forward	Seattle Sounders	1
	Antonio López Midfielder	América	1
	Danny Leyva Midfielder	Seattle Sounders	1
	Joe Scally Defender	New York City	1
	Jordan Sierra Midfielder	Tigres	1
	Alexander Roldan Midfielder	Seattle Sounders	1
	Rubén Marroquín Defender	Alianza San Salvador	1
	Matheus Rossetto Midfielder	Atlanta United FC	1
	Matías Garrido Midfielder	Olimpia de Tegucigalpa	1
	Orji Okwonkwo Forward	Montreal Impact	1
	Mohammad Monir Defender	Los Angeles FC	1
	Gary Mackay-Steven Midfielder	New York City	1
	Ibarra Midfielder	Seattle Sounders	1
	Izaguirre Defender	Motagua	1
	Jesús Medina Midfielder	New York City	1
	Andrés Ibargüen Midfielder	América	1
	Omar Ezequiel Browne Zuniga Forward	San Carlos	1
	Jeff Larentowicz Midfielder	Atlanta United FC	1
	Fernando Gonzalez Midfielder	América	1
	Luis Quiñónes Forward	Tigres	1
	Rubilio Castillo Forward	Motagua	1
	Sebastien Ibeagha Defender	New York City	1
	Josué Domínguez Forward	Cruz Azul	1
	Santiago Giménez Forward	Cruz Azul	1
	Brook Lennon Defender	Atlanta United FC	1
	Jonathan Rodríguez Forward	Cruz Azul	1
	Saúl Zamora Midfielder	León FC	1
	Isaac Portillo Midfielder	Alianza San Salvador	1
	Cristian Martinez Midfielder	San Carlos	1
	Bladimir Díaz Forward	Comunicaciones	1
	Barrantes Midfielder	Saprissa	1
	Harriott Defender	Portmore	1
	Esteban Ramírez Midfielder	San Carlos	1
	José Pinto Forward	Olimpia de Tegucigalpa	1
	Max Urruti Forward	Montreal Impact	1
	Óscar Rodríguez Midfielder	Alianza San Salvador	1
	Juan Vicente Solís Forward	San Carlos	1
	Bryce Duke Midfielder	Los Angeles FC	1
	Rashid Chirino Forward	San Carlos	1
	Cleon Pryce Forward	Portmore	1
	Carlos Castrillo Defender	Comunicaciones	1
	Fredy Thompson Midfielder	Comunicaciones	1
	Revaldo Mitchell Forward	Portmore	1
	Julio Cruz Forward	San Carlos	1
	Solomon Defender	Portmore	1
	Chavany Willis Midfielder	Portmore	1
	Kevon Adrian Farquharson Midfielder	Portmore	1
	Carlos Mejía Defender	Comunicaciones	1
	Edwin Rodriguez Midfielder	Olimpia de Tegucigalpa	1
	Yael López Defender	Saprissa	1
	Alex Güity Goalkeeper	Olimpia de Tegucigalpa	1