Wednesday 23 of September

• Finished

  New England Revolution

  3 - 1

  Montreal Impact

  Bazakos

  Terry Jr.

  Gillette Stadium
• Finished

  Atlanta United FC

  1 - 0

  FC Dallas

  Ford

  Gonzalez

  Mercedes-Benz Stadium
• Finished

  New York City

  0 - 1

  Toronto FC

  Dickerson

  Penso

  Red Bull Arena
• Finished

  Sporting Kansas City

  1 - 2

  Orlando City

  Rivas

  Radford

  Children's Mercy Park
• Finished

  Chicago Fire

  4 - 0

  Houston Dynamo

  de Oliveira

  Gantar

  Soldier Field
• Finished

  Columbus Crew

  2 - 1

  Minnesota United FC

  Elfath

  Stoica

  Historic Crew Stadium
• Finished

  FC Cincinnati

  0 - 0

  Philadelphia Union

  Gonzales Jr.

  Grajeda

  Nippert Stadium
• Finished

  Inter Miami CF

  1 - 4

  New York Red Bulls

  Chilowicz

  Villarreal

  Chase Stadium
• Finished

  Nashville SC

  1 - 0

  DC United

  Penso

  Kelly

  Nissan Stadium, Nashville
• Finished

  Colorado Rapids

  5 - 0

  San José Earthquakes

  Fischer

  Badawi

  Dick's Sporting Goods Park
• Finished

  Real Salt Lake

  2 - 0

  Los Angeles Galaxy

  Petrescu

  Jurisevic

  America First Field
• Finished

  Portland Timbers

  1 - 0

  Seattle Sounders

  Chapman

  Touchan

  Providence Park
• Finished

  Los Angeles FC

  6 - 0

  Vancouver Whitecaps

  Vazquez

  Stott

  BMO Stadium