Three Spanish sides into Europa League quarter-finals
Another successful night across the continent saw Villarreal, Sevilla and Athletic qualify for the next round, meaning Spain have 6 sides left in Europe in the two competitions.
Spanish sides had yet another successful night in Europe, with just one team eliminated, Valencia, and that in a match against other Spanish opposition, Athletic Bilbao.
Gary Neville's side were sent crashing out after they lost their last-16 tie to Spanish rivals Athletic on away goals despite winning the second leg 2-1.
Valencia had been trailing 1-0 after last week's first leg at San Mamés but looked to have turned the tie around when they went two goals up in the first half at the Mestalla.
Santi Mina got the first goal on the night in the 13th minute, following in to score after Alvaro Negredo's effort had been saved by Iago Herrerin.
Aderlan Santos then headed home the second eight minutes before the interval, but beaten 2012 finalists Athletic struck the decisive away goal 14 minutes from the end.
The inevitable Aritz Aduriz got the goal, his eighth in nine Europa League games this season, and his 31st altogether, after a superb flick-on by Raul Garcia (one to seek out on a popular internet video site, it's not to be missed).
Holders Sevilla remain in with a chance of winning the Europa League for the third year running, and fifth time in 11 seasons, after beating Swiss champions Basel 3-0.
After a goalless first leg, Basel were looking to keep alive their hopes of reaching a final that will be played in their own stadium, but Sevilla have a fearsome home record and Adil Rami put them ahead before fellow Frenchman Kevin Gameiro added a quick-fire brace.
Villarreal are also through after beating Bayer Leverkusen 2-0 on aggregate following a 0-0 draw in the second leg in Germany.
That means three Spanish sides in the last eight, and six left in Europe altogether. In contrast, Italian interest in European competition is at an end after Lazio were humbled 3-0 by Sparta Prague in Rome.
Captain Borek Dockal put Sparta in front and Ladislav Krejci and Lukas Julis added further goals before the break to take the Czech side through 4-1 on aggregate.
Liverpool meanwhile eased past Manchester United to seal their place in the draw for the quarter-finals of the Europa League, where Borussia Dortmund and holders Sevilla are looking like the teams to beat.
Jurgen Klopp's side saw off old rivals Manchester United as a 1-1 second-leg draw at Old Trafford on Thursday saw them win their last-16 tie 3-1 on aggregate.
United had it all to do after losing last week's first leg 2-0 but they were given hope when Anthony Martial scored from the penalty spot just past the half-hour mark after the Frenchman was fouled in the box by Nathaniel Clyne.
However, Daniel Sturridge struck the bar from a free-kick before Philippe Coutinho scored a superb goal for Liverpool just prior to the break, cutting in from the left and chipping past David de Gea.
That left United needing three more goals to stay in Europe and they never looked like doing enough in the second half to prevent an exit that only piles more pressure on manager Louis van Gaal.
Klopp's old side Dortmund eased through with the prolific Pierre-Emerick Aubameyang scoring twice in their 2-1 win away to Tottenham Hotspur at White Hart Lane that saw them win the tie 5-1 on aggregate.
The Gabon striker lashed a swerving long-range strike past Hugo Lloris on 24 minutes and then added another in the second half to take his tally for the season to 35 goals.
Son Heung-Min pulled one back for Spurs, who are now left to focus on their Premier League title challenge.
The 2009 UEFA Cup winners Shakhtar Donetsk also advanced, Eduardo's late goal securing a 1-0 win away to Anderlecht in Belgium that took the Ukrainians through 4-1 on aggregate.
The quarter-final line-up was completed by Portuguese side Braga, after the 2011 runners-up overturned a 1-0 first-leg deficit by beating Fenerbahce 4-1 as the Turkish giants ended the game with just eight men.
Ahmed Hassan put Braga ahead only for Alper Potuk to grab an away goal for Fenerbahce.
However, Mehmet Topal was sent off after conceding a penalty that was converted by Josue, and Nikola Stoiljkovic put the hosts ahead in the tie on 74 minutes.
Rafa Silva added another goal for Braga while Fenerbahce also had Potuk and Volkan Sen red-carded.