Research suggests that people with this blood type are more likely to reach 100 years of age

A new line of genetic research has revealed a potential link between blood type and longevity—and all signs point to one standout: blood type O.

Evidence suggests that individuals with this blood type not only face a lower risk of cardiovascular disease and certain cancers, but also appear in disproportionately high numbers among those who live past 100.

According to research reported by Time magazine, blood type O is associated with a reduced risk of heart attacks and strokes—two of the leading causes of death worldwide. These findings are further supported by studies linking this blood type to a lower incidence of various cancers, which together may directly contribute to a longer life expectancy.

“Disease resistance, both in the blood and the immune system, is essential for building a strategy for longevity. And having type O enhances that,” said Professor Stuart Kim, a geneticist at Stanford University. To explore this link, Kim and his team analyzed the DNA of more than 800 centenarians and around 5,400 people over the age of 90, identifying common genetic patterns among those who reached exceptional ages.

Among the most influential genes they identified were CDKN2B, which regulates cell division; APOE, which is linked to Alzheimer’s disease; and SH2B3, which may play a direct role in aging. Notably, the ABO gene—responsible for determining blood type—also emerged, with the O variant appearing frequently among the longest-lived individuals.

Despite these promising findings, the researchers stress that genetics is just one part of the longevity equation. “It’s not enough to have good genes,” Kim emphasized. Scientific evidence consistently shows that factors such as a balanced diet, regular physical activity, emotional well-being, and access to preventive health care are just as vital for reaching a long and healthy old age.

While more research is needed to fully understand the mechanisms at play, the evidence so far supports the idea that blood type O may offer a biological advantage. Still, when it comes to the secret of a long life, the age-old balance between nature and nurture remains the key ingredient.

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