Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Igor Gomes Midfielder	Atlético Mineiro	9Player was brought on as a substitute
2	Antonio Galeano Forward	Cerro Porteño	8
	Richard Rios Midfielder	Palmeiras	8
3	Braian Samudio Forward	Cerro Porteño	7
	Irven Ávila Forward	Sporting Cristal	7
	Martín Távara Midfielder	Sporting Cristal	7
	Carlos De Pena Midfielder	Internacional	7
	Breno Lopes Forward	Palmeiras	7
	Lelê Forward	Fluminense	7
4	Enzo Giménez Midfielder	Cerro Porteño	6
	Damián Bobadilla Midfielder	Cerro Porteño	6
	Hyoran Midfielder	Atlético Mineiro	6
	Miguel Merentiel Forward	Boca Juniors	6
	John Kennedy Forward	Fluminense	6
	Leonardo Heredia Midfielder	Argentinos Juniors	6
	Carmelo Algarañaz Forward	Bolívar	6
	Everton Forward	Flamengo	6
	Patrik Mercado Midfielder	Independiente del Valle	6
	Vinicius Midfielder	Fluminense	6
	Luiz Adriano Forward	Internacional	6
	Hugo Quintana Midfielder	Olimpia	6
	Facundo Bruera Forward	Olimpia	6
	Agustín Palavecino Midfielder	River Plate	6
	Diego Torres Midfielder	Olimpia	6
	Junior Arias Forward	The Strongest	6
5	Vargas Forward	Atlético Mineiro	5
	Joao Grimaldo Forward	Sporting Cristal	5
	Edwin Cetre Forward	Independiente Medellín	5
	Enmerson Batalla Forward	Independiente Medellín	5
	Washington Corozo Forward	Sporting Cristal	5
	Adrián Ascues Midfielder	Sporting Cristal	5
	Deiner Quiñónez Midfielder	Independiente Medellín	5
	Jonatan Bauman Forward	Barcelona de Guayaquil	5
	Ramiro Vaca Midfielder	Bolívar	5
	Michael Carcelén Midfielder	Aucas	5
	Exequiel Zeballos Forward	Boca Juniors	5
	Miguel Villarroel Forward	Bolívar	5
	Nicolás Valentini Defender	Boca Juniors	5
	Javier Uzeda Midfielder	Bolívar	5
	Martinelli Midfielder	Fluminense	5
	Moreno Forward	Independiente del Valle	5
	Martín Barrios Midfielder	Liverpool (Montevideo)	5
	Igor Gomes Defender	Internacional	5
	Pedro Henrique Forward	Internacional	5
	Lucca Forward	Internacional	5
	Bruno Damiani Forward	Nacional	5
	Jhon Jhon Midfielder	Palmeiras	5
	Endrick Forward	Palmeiras	5
	Pablo Solari Forward	River Plate	5
	Fabinho Midfielder	Palmeiras	5
	Baltasar Rodríguez Midfielder	Racing Club	5
	Bruno Henrique Midfielder	Internacional	5
	Lucas Janson Forward	Boca Juniors	5
	Marlon Santos Defender	Fluminense	5
	Leandro Rodríguez Defender	Monagas	5
6	Otavio Henrique Passos Santos Midfielder	Atlético Mineiro	4
	Jader Valencia Forward	Millonarios	4
	Leandro Sosa Midfielder	Sporting Cristal	4
	Leonardo Díaz Defender	Sporting Cristal	4
	Gustavo Caballero Forward	Nacional Asunción	4
	David Loaiza Forward	Independiente Medellín	4
	Gustavo Asprilla Forward	El Nacional	4
	Patrick Midfielder	Atlético Mineiro	4
	Juan Manuel García Forward	Huracán	4
	Guilherme Forward	Fortaleza	4
	Franco Zanelatto Midfielder	Alianza Lima	4
	Thiago Nuss Forward	Argentinos Juniors	4
	Gastón Verón Forward	Argentinos Juniors	4
	Jordan Rezabala Midfielder	Aucas	4
	Luis Vázquez Forward	Boca Juniors	4
	Roberto Ordoñez Forward	Aucas	4
	Gabriel Poveda Forward	Bolívar	4
	Vitor Midfielder	Athletico Paranaense	4
	Jesús Sagredo Defender	Bolívar	4
	Hugo Moura Midfielder	Athletico Paranaense	4
	Benedetto Forward	Boca Juniors	4
	Victor Hugo Midfielder	Flamengo	4
	Agustín Rodríguez Forward	Barcelona de Guayaquil	4
	Luciano Sánchez Defender	Argentinos Juniors	4
	Marcelo Weigandt Defender	Boca Juniors	4
	Geisson Perea Defender	Deportivo Pereira	4
	Vicente Pizarro Midfielder	Colo-Colo	4
	Kevin Rodríguez Forward	Independiente del Valle	4
	Fidel Martínez Midfielder	Barcelona de Guayaquil	4
	Gabriel Pirani Midfielder	Fluminense	4
	Ángel Romero Forward	Corinthians	4
	Gustavo Cortez Defender	Independiente del Valle	4
	Alexandre Alemão Forward	Internacional	4
	Iván Ramírez Defender	Libertad	4
	Marcos Montiel Midfielder	Nacional	4
	Andrés Vilches Forward	Ñublense	4
	Ramón Martínez Midfielder	Olimpia	4
	Jorge Henríquez Midfielder	Ñublense	4
	Enzo Díaz Forward	Patronato	4
	José Paradela Midfielder	River Plate	4
	Brian Montenegro Forward	Olimpia	4
	Jonathan Galván Defender	Racing Club	4
	Miguel Borja Forward	River Plate	4
	José López Forward	Palmeiras	4
7	Bruno Barja Forward	Boston River	3

Copa Libertadores

Players Player was brought on as a substitute