Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Danilo Pinheiro Midfielder	Botafogo	10Player was brought on as a substitute
	Lucas Hernández Defender	Peñarol	10
2	Mateo Ponte Defender	Botafogo	9
	Emiliano Amor Defender	Colo-Colo	9
3	Diego Zabala Midfielder	Nacional	8
	Cristian Zavala Forward	Colo-Colo	8
	Guillermo Paiva Forward	Colo-Colo	8
4	Joe Abrigo Forward	Palestino	7
	Pablo Palacio Midfielder	Palestino	7
	Gustavo Nunes Forward	Grêmio	7
	Diego Erazo Forward	Nacional	7
5	Jordán Santacruz Midfielder	Nacional Asunción	6
	Jeremía Recoba Midfielder	Nacional	6
	Gustavo Aguilar Forward	Libertad	6
	Lanzini Midfielder	River Plate	6
	Vinicius Midfielder	Fluminense	6
	Igor Gomes Midfielder	Atlético Mineiro	6
	Diego Dorregaray Forward	Universitario de Deportes	6
	Rodrigo Nestor Bertalia Midfielder	São Paulo	6
	Nahuel Bustos Forward	San Lorenzo	6
6	Marcal Defender	Botafogo	5
	Tiquinho Forward	Botafogo	5
	Damián Pizarro Forward	Colo-Colo	5
	Junior Marabel Forward	Palestino	5
	Federico Santander Forward	Nacional	5
	Christian Ebere Forward	Nacional	5
	Gregore Midfielder	Botafogo	5
	Michel Araújo Midfielder	São Paulo	5
	Franco Lobos Forward	Cobresal	5
	Ezequiel Barco Midfielder	River Plate	5
	Rony Forward	Palmeiras	5
	Franco Mastantuono Midfielder	River Plate	5
	André Silva Forward	São Paulo	5
	Antonio Carlos Defender	Fluminense	5
	Franco Nicola Forward	Liverpool (Montevideo)	5
	Mauro Méndez Forward	Estudiantes de La Plata	5
	Jean Castillo Forward	Deportivo Táchira	5
	Sebastián Sáez Forward	Huachipato	5
	Yaimar Medina Midfielder	Independiente del Valle	5
	Renzo Machado Forward	Liverpool (Montevideo)	5
	Nathan Fernandes Forward	Grêmio	5
	Renzo López Forward	Independiente del Valle	5
	Bruno Miranda Forward	The Strongest	5
	Vargas Forward	Atlético Mineiro	5
	Marco Pérez Forward	Junior	5
	Luiz Araujo Forward	Flamengo	5
	Erick Forward	São Paulo	5
	Gastón Ramírez Midfielder	Peñarol	5
	Ignacio Sosa Midfielder	Peñarol	5
	Óscar Romero Midfielder	Botafogo	5
	Facundo Batista Forward	Peñarol	5
7	Moisés Paniagua Forward	Always Ready	4
	Danilo Midfielder	Botafogo	4
	Vicente Pizarro Midfielder	Colo-Colo	4
	Marco Bolados Forward	Colo-Colo	4
	Bryan Véjar Midfielder	Palestino	4
	Felipe Chamorro Midfielder	Palestino	4
	Ignacio Laquintana Midfielder	RB Bragantino	4
	Carlos Cermeño Midfielder	Academia Puerto Cabello	4
	Marcelo González Midfielder	Nacional Asunción	4
	Gastón González Forward	Nacional	4
	Pereyra Midfielder	Nacional	4
	Bentancourt Forward	Nacional	4
	Camilo Mayada Midfielder	Peñarol	4
	Rodrigo Villagra Midfielder	River Plate	4
	Matías Galarza Fonda Midfielder	Talleres de Córdoba	4
	Diego Rodríguez Midfielder	Liverpool (Montevideo)	4
	Alisson Midfielder	Atlético Mineiro	4
	Henry Vaca Forward	Bolívar	4
	Keny Arroyo Midfielder	Independiente del Valle	4
	Álvaro Campuzano Midfielder	Libertad	4
	Gabriel Barbosa Forward	Flamengo	4
	Steven Rodríguez Forward	Junior	4
	Agustín González Midfielder	Liverpool (Montevideo)	4
	Pablo Solari Forward	River Plate	4
	Ayrton Defender	Flamengo	4
	José López Forward	Palmeiras	4
	Leonardo Sequeira Forward	Peñarol	4
	Giuliano Galoppo Midfielder	São Paulo	4
	Facundo Colidio Forward	River Plate	4
	Federico Carrizo Midfielder	Cerro Porteño	4
	Nicolás Fonseca Midfielder	River Plate	4
	Jairo Concha Midfielder	Universitario de Deportes	4
	Richard Figueroa Forward	Caracas	4
	Otavio Henrique Passos Santos Midfielder	Atlético Mineiro	4
	Gabriel Aguayo Midfielder	Cerro Porteño	4
	Mayke Defender	Palmeiras	4
	Cadu Forward	Atlético Mineiro	4
	Luca Martínez Forward	Rosario Central	4
	Lorran Midfielder	Flamengo	4
	Hugo Martínez Midfielder	Libertad	4
	Gastón Lezcano Forward	Cobresal	4
	Adam Bareiro Forward	River Plate	4
	Matheus Martins Forward	Botafogo	4
8	Stevy Okitokandjo Forward	Academia Puerto Cabello	3
	Julio Herrera Midfielder	Always Ready	3
	Janderson Forward	Botafogo	3
	Ismael Benegas Defender	Nacional Asunción	3
	Facundo Velazco Midfielder	Nacional Asunción	3
	Tiago Caballero Forward	Nacional Asunción	3

Copa Libertadores

Players Player was brought on as a substitute