Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Diego Zabala Midfielder	Nacional	8Player was brought on as a substitute
	Emiliano Amor Defender	Colo-Colo	8
2	Joe Abrigo Forward	Palestino	7
	Pablo Palacio Midfielder	Palestino	7
3	Mateo Ponte Defender	Botafogo	6
	Danilo Pinheiro Midfielder	Botafogo	6
	Jordán Santacruz Midfielder	Nacional Asunción	6
	Gustavo Aguilar Forward	Libertad	6
	Diego Dorregaray Forward	Universitario de Deportes	6
4	Damián Pizarro Forward	Colo-Colo	5
	Junior Marabel Forward	Palestino	5
	Christian Ebere Forward	Nacional	5
	Federico Santander Forward	Nacional	5
	Jeremía Recoba Midfielder	Nacional	5
	Gregore Midfielder	Botafogo	5
	Igor Gomes Midfielder	Atlético Mineiro	5
	Franco Lobos Forward	Cobresal	5
	Jean Castillo Forward	Deportivo Táchira	5
	Luiz Araujo Forward	Flamengo	5
	Sebastián Sáez Forward	Huachipato	5
	Yaimar Medina Midfielder	Independiente del Valle	5
	Renzo López Forward	Independiente del Valle	5
	Renzo Machado Forward	Liverpool (Montevideo)	5
	Franco Nicola Forward	Liverpool (Montevideo)	5
	Lucas Hernández Defender	Peñarol	5
	Ezequiel Barco Midfielder	River Plate	5
	Diego Erazo Forward	San Lorenzo	5
	Erick Forward	São Paulo	5
5	Bryan Véjar Midfielder	Palestino	4
	Vicente Pizarro Midfielder	Colo-Colo	4
	Moisés Paniagua Forward	Always Ready	4
	Felipe Chamorro Midfielder	Palestino	4
	Ignacio Laquintana Midfielder	RB Bragantino	4
	Cristian Zavala Midfielder	Colo-Colo	4
	Carlos Cermeño Midfielder	Academia Puerto Cabello	4
	Marcelo González Midfielder	Nacional Asunción	4
	Gastón González Forward	Nacional	4
	Bentancourt Forward	Nacional	4
	Guillermo Paiva Forward	Colo-Colo	4
	Richard Figueroa Forward	Caracas	4
	Federico Carrizo Midfielder	Cerro Porteño	4
	Gabriel Aguayo Midfielder	Cerro Porteño	4
	Gastón Lezcano Forward	Cobresal	4
	Mauro Méndez Forward	Estudiantes de La Plata	4
	Lorran Midfielder	Flamengo	4
	Gustavo Nunes Midfielder	Grêmio	4
	Nathan Fernandes Forward	Grêmio	4
	Keny Arroyo Midfielder	Independiente del Valle	4
	Marco Pérez Forward	Junior	4
	Álvaro Campuzano Midfielder	Libertad	4
	Hugo Martínez Midfielder	Libertad	4
	Agustín González Midfielder	Liverpool (Montevideo)	4
	Diego Rodríguez Midfielder	Liverpool (Montevideo)	4
	Mayke Defender	Palmeiras	4
	Rony Forward	Palmeiras	4
	José López Forward	Palmeiras	4
	Ignacio Sosa Midfielder	Peñarol	4
	Luca Martínez Forward	Rosario Central	4
	Giuliano Galoppo Midfielder	São Paulo	4
	Matías Galarza Midfielder	Talleres de Córdoba	4
	Nahuel Bustos Forward	Talleres de Córdoba	4
	Bruno Miranda Forward	The Strongest	4
	Jairo Concha Midfielder	Universitario de Deportes	4
	Óscar Romero Midfielder	Botafogo	4
6	Misael Dávila Midfielder	Palestino	3
	Guilherme Defender	RB Bragantino	3
	Julio Herrera Midfielder	Always Ready	3
	Ismael Benegas Defender	Nacional Asunción	3
	Stevy Okitokandjo Forward	Academia Puerto Cabello	3
	Facundo Velazco Midfielder	Nacional Asunción	3
	Janderson Forward	Botafogo	3
	Talisson Forward	RB Bragantino	3
	Jonathan Benítez Forward	Palestino	3
	Tiago Caballero Forward	Nacional Asunción	3
	Ariel Martinez Midfielder	Palestino	3
	Oscar Guillermo Giménez Forward	Sportivo Trinidense	3
	Tomás Rayer Midfielder	Sportivo Trinidense	3
	Eduardo Duarte Defender	Nacional Asunción	3
	Alan Pereira Forward	Sportivo Trinidense	3
	Michael Covea Midfielder	Academia Puerto Cabello	3
	Brian Andrada Forward	Sportivo Trinidense	3
	Lucas Cepeda Midfielder	Colo-Colo	3
	Ayron Del Valle Forward	Always Ready	3
	Mateo Antoni Defender	Nacional	3
	Christian Oliva Midfielder	Nacional	3
	Felipe Cairus Midfielder	Nacional	3
	Franco Zanelatto Midfielder	Alianza Lima	3
	Aldair Fuentes Midfielder	Alianza Lima	3
	Jeriel De Santis Forward	Alianza Lima	3
	Alisson Midfielder	Atlético Mineiro	3
	Vargas Forward	Atlético Mineiro	3
	Cadu Forward	Atlético Mineiro	3
	Janner Corozo Midfielder	Barcelona de Guayaquil	3
	Dixon Arroyo Midfielder	Barcelona de Guayaquil	3
	Braian Oyola Midfielder	Barcelona de Guayaquil	3
	Lucas Chávez Midfielder	Bolívar	3
	Henry Vaca Forward	Bolívar	3
	Lucciano Reinoso Forward	Caracas	3
	Wílder Viera Midfielder	Cerro Porteño	3
	Fernando Fernández Forward	Cerro Porteño	3

Copa Libertadores

Players Player was brought on as a substitute