Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Moi Gómez Forward	Villarreal	10Player was brought on as a substitute
2	G. Gaudino Midfielder	Young Boys	9
3	Bartol Franjic Midfielder	Dinamo Zagreb	8
	Ondrej Lingr Midfielder	Slavia Prague	8
4	Mohamed Elneny Midfielder	Arsenal	7
	Erling Knudtzon Defender	Molde	7
	Eteki Midfielder	Granada CF	7
	Lukas Masopust Midfielder	Slavia Prague	7
	Felix Mambimbi Forward	Young Boys	7
	Nana Ampomah Forward	Royal Antwerp	7
	Yeremy Pino Forward	Villarreal	7
	Believe Atiemwen Forward	Dinamo Zagreb	7
5	Barrenetxea Forward	Real Sociedad	6
	Dani Ceballos Midfielder	Arsenal	6
	Martinelli Forward	Arsenal	6
	Willian Forward	Arsenal	6
	Theoson Siebatcheu Forward	Young Boys	6
	Steven Bergwijn Forward	Tottenham Hotspur	6
	Ibrahim Benjanim Traore Midfielder	Slavia Prague	6
	Lorenzo Pellegrini Midfielder	Roma	6
	Mayoral Forward	Roma	6
	Brian Brobbey Forward	Ajax	6
	Idrissi Forward	Ajax	6
6	Rafael Leao Forward	Milan	5
	Tierney Defender	Arsenal	5
	Mathis Bolly Forward	Molde	5
	Bernard Tekpetey Forward	Ludogorets Razgrad	5
	Willian José Forward	Real Sociedad	5
	Ernest Asante Forward	Omonia Nicosia	5
	Ahmed Ahmedov Forward	CSKA Sofia	5
	S. Yateke Forward	HNK Rijeka	5
	Jorge Molina Forward	Granada CF	5
	Jon Bautista Forward	Real Sociedad	5
	Buta Defender	Royal Antwerp	5
	Luis Suárez Forward	Granada CF	5
	Kristijan Bistrovic Midfielder	CSKA Moscow	5
	Swiderski Forward	PAOK Salonika	5
	Rabusic Forward	Slovan Liberec	5
	Gonzalo Villar Midfielder	Roma	5
	André Horta Midfielder	Sporting Braga	5
	Guilherme Schettine Forward	Sporting Braga	5
	M. Perović Forward	Zorya Luhansk	5
	Hojbjerg Midfielder	Tottenham Hotspur	5
	Álex Baena Forward	Villarreal	5
	N. Rnic Defender	RZ Pellets WAC	5
	Folarin Balogun Forward	Arsenal	5
	Mata Midfielder	Manchester United	5
7	Rafa Silva Forward	Benfica	4
	Alberto Soro Forward	Granada CF	4
	Ayoze Pérez Forward	Leicester City	4
	Seferovic Forward	Benfica	4
	Hussain Midfielder	Molde	4
	Marko Tolic Midfielder	Dinamo Zagreb	4
	Machís Forward	Granada CF	4
	Tomas Rogic Midfielder	Celtic	4
	Isaac Lihadji Forward	Lille	4
	Katcharava Forward	Lech Poznan	4
	Mohammed Awaed Forward	Lech Poznan	4
	Moussa Diaby Forward	Bayer 04 Leverkusen	4
	Henrique Forward	CSKA Sofia	4
	Dino Peric Defender	Dinamo Zagreb	4
	Varenne Forward	Hapoel Be'er Sheva	4
	Boubakary Soumare Midfielder	Lille	4
	Reikan Midfielder	Maccabi Tel Aviv	4
	Dogbole Niangbo Midfielder	KAA Gent	4
	Nayair Tiknizyan Midfielder	CSKA Moscow	4
	Mkhitaryan Midfielder	Roma	4
	Dan Ndoye Forward	Nice	4
	Mauro Junior Defender	PSV	4
	Veljko Nikolić Midfielder	Crvena Zvezda	4
	Yilmaz Forward	Lille	4
	Eduardo Guerrero Forward	Maccabi Tel Aviv	4
	Adolfo Gaich Forward	CSKA Moscow	4
	Gavranovic Forward	Dinamo Zagreb	4
	Dzeko Forward	Roma	4
	Nick Blackman Forward	Maccabi Tel Aviv	4
	Zakaria Aboukhal Forward	AZ	4
	Frank Boya Midfielder	Royal Antwerp	4
	Thomas Goiginger Forward	LASK	4
	Vasyl Kravets Defender	Lech Poznan	4
	Lirim Kastrati I Forward	Dinamo Zagreb	4
	Reinildo Mandava Defender	Lille	4
	Brahim Diaz Midfielder	Milan	4
	Koné Forward	Sivasspor	4
	Theodosis Macheras Forward	AEK Athens	4
	Puertas Forward	Granada CF	4
	Luiz Araujo Forward	Lille	4
	Hirving Lozano Forward	Napoli	4
	Bruno Peres Defender	Roma	4
	Njegos Petrovic Midfielder	Crvena Zvezda	4
	Sargis Adamyan Forward	TSG Hoffenheim	4
	Jan Matousek Midfielder	Slovan Liberec	4
	Vincent Sierro Midfielder	Young Boys	4
	Verstraete Midfielder	Royal Antwerp	4
	Meschack Elia Forward	Young Boys	4
	Carlos Forward	Tottenham Hotspur	4
	Alcácer Forward	Villarreal	4
	Kramaric Forward	TSG Hoffenheim	4
	Avenatti Forward	Standard Liège	4
	Fernando Niño Forward	Villarreal	4

Europa League

Players Player was brought on as a substitute