Players Substitute appearances

Pos.	Player	Team	Total
1	Politano Forward	Inter	23Substitute appearances
2	Poli Midfielder	Bolonia	19
3	João Pedro Midfielder	Cagliari	18
4	Daniele Baselli Midfielder	Torino	17
5	Benassi Midfielder	Fiorentina	16
6	Gerson Midfielder	Fiorentina	15
	Luca Siligardi Forward	Parma	15
	Hakan Calhanoglu Midfielder	Milan	15
	Gastón Ramírez Midfielder	Sampdoria	15
	Luis Alberto Midfielder	Lazio	15
	Caicedo Forward	Lazio	15
7	Alejandro Gómez Midfielder	Atalanta	14
	Djuricic Midfielder	Sassuolo	14
	Karol Linetty Midfielder	Sampdoria	14
	Artur Ionita Midfielder	Cagliari	14
	Acquah Midfielder	Empoli	14
	Andrea Petagna Forward	SPAL	14
	Ignacio Pussetto Forward	Udinese	14
8	Iago Forward	Torino	13
	Hamed Junior Traore Midfielder	Empoli	13
	Scozzarella Midfielder	Parma	13
	Valoti Midfielder	SPAL	13
	Camillo Ciano Forward	Frosinone	13
	Justin Kluivert Forward	Roma	13
9	Defrel Forward	Sampdoria	12
	Stefano Sensi Midfielder	Sassuolo	12
	De Silvestri Defender	Torino	12
	Matuidi Midfielder	Juventus	12
	Cengiz Ünder Midfielder	Roma	12
	Quagliarella Forward	Sampdoria	12
	Federico Di Francesco Forward	Sassuolo	12
	Federico Bernardeschi Forward	Juventus	12
	Suso Forward	Milan	12
	Giovanni Simeone Forward	Fiorentina	12
	Caprari Forward	Sampdoria	12
	Babacar Forward	Sassuolo	12
	Mirallas Forward	Fiorentina	12
	Josip Ilicic Midfielder	Atalanta	12
10	Darko Lazovic Midfielder	Genoa	11
	Radu Defender	Lazio	11
	Pjanić Midfielder	Juventus	11
	Diego Farias Forward	Empoli	11
	Nainggolan Midfielder	Inter	11
	Rade Krunic Midfielder	Empoli	11
	Nicolo Zaniolo Midfielder	Roma	11
	Cigarini Midfielder	Cagliari	11
11	Daniel Bessa Midfielder	Genoa	10
	Lorenzo Pellegrini Midfielder	Roma	10
	Missiroli Midfielder	SPAL	10
	Zielinski Midfielder	Nápoles	10
	Ansaldi Defender	Torino	10
	Badelj Midfielder	Lazio	10
	Insigne Forward	Nápoles	10
	Remo Freuler Midfielder	Atalanta	10
	Mertens Forward	Nápoles	10
	Arkadiusz Milik Forward	Nápoles	10
	Riccardo Saponara Midfielder	Sampdoria	10
	Hetemaj Midfielder	Chievo	10
	Meggiorini Forward	Chievo	10
	Manuel Locatelli Midfielder	Sassuolo	10
	Milinkovic-Savic Midfielder	Lazio	10
	Pasalic Midfielder	Atalanta	10
12	Valzania Midfielder	Frosinone	9
	Matias Vecino Midfielder	Inter	9
	Lucas Paquetá Midfielder	Milan	9
	Floccari Forward	SPAL	9
	Verdi Forward	Nápoles	9
	Campbell Forward	Frosinone	9
	Pandev Forward	Genoa	9
	Filip Bradaric Midfielder	Cagliari	9
	Dzemaili Midfielder	Bolonia	9
	Francesco Cassata Midfielder	Frosinone	9
	Fabio Ceravolo Forward	Parma	9
	Maiello Midfielder	Frosinone	9
	Schiattarella Midfielder	SPAL	9
	Edimilson Fernandes Midfielder	Fiorentina	9
	Berhami Midfielder	Udinese	9
	Antonio La Gumina Forward	Empoli	9
	Borja Valero Midfielder	Inter	9
	Mariusz Stepinski Forward	Chievo	9
	Patrik Schick Forward	Roma	9
	Robin Gosens Defender	Atalanta	9
	Gervinho Forward	Parma	9
	Cristian Kouame Forward	Genoa	9
	Lulic Midfielder	Lazio	9
13	Mathas Svanberg Midfielder	Bolonia	8
	Chukwuma Midfielder	Chievo	8
	Chuka Forward	Udinese	8
	Hidde ter Avest Defender	Udinese	8
	Duván Zapata Forward	Atalanta	8
	Gianluca Mancini Defender	Atalanta	8
	Krzysztof Piatek Forward	Milan	8
	El Shaarawy Forward	Roma	8
	Perisic Midfielder	Inter	8
	Daniel Ciofani Forward	Frosinone	8
	Hiljemark Midfielder	Genoa	8
	Emanuel Vignato Midfielder	Chievo	8
	Andrea Pinamonti Forward	Frosinone	8
	Souahilo Meité Midfielder	Torino	8
	Mandžukic Forward	Juventus	8