Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Pedro Forward	Lazio	28Player was brought on as a substitute
2	Davide Frattesi Midfielder	Internazionale	26
	Samuele Mulattieri Forward	Sassuolo	26
3	Milik Forward	Juventus	25
4	Matias Vecino Midfielder	Lazio	23
	Giacomo Raspadori Forward	Napoli	23
	Carlos Augusto Defender	Internazionale	23
	Roberto Piccoli Forward	Lecce	23
5	Noah Okafor Forward	Milan	22
	Arnautovic Forward	Internazionale	22
6	Valentín Carboni Midfielder	Monza	21
	Sansone Forward	Lecce	21
7	Samuel Iling Forward	Juventus	20
	Giovanni Simeone Forward	Napoli	20
	Azmoun Forward	Roma	20
	Jesper Lindstrom Midfielder	Napoli	20
8	Caleb Ekuban Forward	Genoa	19
	Valentín Castellanos Forward	Lazio	19
	Mateusz Legowski Midfielder	Salernitana	19
9	Tim Weah Midfielder	Juventus	18
	Success Forward	Udinese	18
	Kenan Yildiz Forward	Juventus	18
	M'Bala Nzola Forward	Fiorentina	18
	Matteo Cancellieri Forward	Empoli	18
10	Jacopo Fazzini Midfielder	Empoli	17
	Rolando Mandragora Midfielder	Fiorentina	17
	Kristjan Asllani Midfielder	Internazionale	17
	Cristian Volpato Midfielder	Sassuolo	17
	Pietro Pellegri Forward	Torino	17
	Jordan Zemura Defender	Udinese	17
	Joao Ferrira Defender	Udinese	17
	Yunus Musah Midfielder	Milan	17
	Alexis Forward	Internazionale	17
11	Luis Muriel Forward	Atalanta	16
	Paulo Defender	Cagliari	16
	Joan González Midfielder	Lecce	16
	Thomas Henry Forward	Hellas Verona	16
	Marvin Cuni Forward	Frosinone	16
	Gustav Isaksen Forward	Lazio	16
	Giovanni Fabbian Midfielder	Bologna	16
12	Miranchuk Midfielder	Atalanta	15
	Benito Viola Midfielder	Cagliari	15
	Blin Midfielder	Lecce	15
	Morten Thorsby Midfielder	Genoa	15
	Jens Cajuste Midfielder	Napoli	15
	Patrick Dorgu Defender	Lecce	15
	Jovic Forward	Milan	15
13	Riccardo Orsolini Forward	Bologna	14
	Leonardo Pavoletti Forward	Cagliari	14
	Pedro Pereira Defender	Monza	14
	El Shaarawy Forward	Roma	14
	Gaetano Pio Oristanio Midfielder	Cagliari	14
	Bonazzoli Forward	Hellas Verona	14
	Uros Racic Midfielder	Sassuolo	14
	Chukwubuikem Ikwuemesi Forward	Salernitana	14
	Lazaro Defender	Torino	14
14	Hans Hateboer Defender	Atalanta	13
	Nikola Moro Midfielder	Bologna	13
	Kacper Urbanski Midfielder	Bologna	13
	Alessandro Di Pardo Defender	Cagliari	13
	Gabriele Zappa Defender	Cagliari	13
	Liberato Cacace Defender	Empoli	13
	Antonin Barak Midfielder	Fiorentina	13
	Cataldi Midfielder	Lazio	13
	Samuele Birindelli Defender	Monza	13
	Edoardo Bove Midfielder	Roma	13
	Nedim Bajrami Midfielder	Sassuolo	13
	Defrel Forward	Sassuolo	13
	Mergim Vojvoda Defender	Torino	13
	Oussama El Azzouzi Midfielder	Bologna	13
	Viktor Kovalenko Midfielder	Empoli	13
15	Lykogiannis Defender	Bologna	12
	Mattia Destro Forward	Empoli	12
	Cristian Kouame Forward	Fiorentina	12
	Guiseppe Caso Forward	Frosinone	12
	Denzel Dumfries Defender	Internazionale	12
	Florenzi Defender	Milan	12
	Nicola Zalewski Midfielder	Roma	12
	Sanabria Forward	Torino	12
	Kingsley Ehizibue Defender	Udinese	12
	Marco Brescianini Midfielder	Frosinone	12
	Strootman Midfielder	Genoa	12
	Emmanuel Gyasi Forward	Empoli	12
	Eldor Shomurodov Forward	Cagliari	12
	Chukwueze Forward	Milan	12
	Daichi Kamada Midfielder	Lazio	12
	Gianluca Scamacca Forward	Atalanta	12
	Dan Ndoye Forward	Bologna	12
	Walid Cheddira Forward	Frosinone	12
	Marcus Pedersen Defender	Sassuolo	12
	Agustín Martegani Midfielder	Salernitana	12
	Kaio Jorge Forward	Frosinone	12
	Maxime López Midfielder	Fiorentina	12
	Klaassen Midfielder	Internazionale	12
	Cyril Ngonge Forward	Napoli	12
	Swiderski Forward	Hellas Verona	12
16	Pasalic Midfielder	Atalanta	11
	Zito Forward	Cagliari	11
	Kean Forward	Juventus	11
	Hysaj Defender	Lazio	11

Serie A

Players Player was brought on as a substitute