Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Raúl García Midfielder	Athletic Club	29Player was brought on as a substitute
2	Kike García Forward	Osasuna	28
3	Ezequiel Ponce Forward	Elche	26
4	Ansu Fati Forward	Barcelona	24
	Stuani Forward	Girona	24
	Falcao Forward	Rayo Vallecano	24
	Abdón Prats Forward	Mallorca	24
5	Portillo Midfielder	Almería	23
6	Correa Forward	Atlético de Madrid	22
	Unai López Midfielder	Rayo Vallecano	22
	Willian José Forward	Real Betis	22
7	Antonio Sánchez Midfielder	Mallorca	21
	Kessié Franck Midfielder	Barcelona	21
8	Oier Zarraga Midfielder	Athletic Club	20
	Joaquín Midfielder	Real Betis	20
	Ramazani Forward	Almería	20
	Pathé Ciss Midfielder	Rayo Vallecano	20
	Saúl Midfielder	Atlético de Madrid	20
	Salvi Midfielder	Rayo Vallecano	20
	Paciencia Forward	Celta de Vigo	20
9	Ferrán Torres Forward	Barcelona	19
10	Iván Alejo Midfielder	Cádiz	18
	Valery Fernández Defender	Girona	18
	Rubén García Midfielder	Osasuna	18
	Hugo Duro Forward	Valencia CF	18
	Morales Forward	Villarreal	18
	Munir Forward	Getafe	18
11	Dyego Sousa Forward	Almería	17
	Josan Midfielder	Elche	17
	Portu Forward	Getafe	17
12	Raúl Guti Midfielder	Elche	16
	Melamed Midfielder	Espanyol	16
	Camavinga Midfielder	Real Madrid	16
	Brasanac Midfielder	Osasuna	16
	Robert Navarro Midfielder	Real Sociedad	16
	Aguado Midfielder	Real Valladolid	16
	José Mari Midfielder	Cádiz	16
	Marco Asensio Forward	Real Madrid	16
	Amath Forward	Mallorca	16
	Carlos Fernández Forward	Real Sociedad	16
	Álex Baena Midfielder	Villarreal	16
	Juan Latasa Forward	Getafe	16
13	Aleix Vidal Defender	Espanyol	15
	Ángel Algobia Midfielder	Getafe	15
	Arnau Martínez Midfielder	Almería	15
	Eguaras Midfielder	Almería	15
	Pablo Barrios Rivas Midfielder	Atlético de Madrid	15
	Franco Cervi Midfielder	Celta de Vigo	15
	Ángel Forward	Mallorca	15
	Grenier Midfielder	Mallorca	15
	Suso Midfielder	Sevilla	15
	Lato Defender	Valencia CF	15
	Trigueros Midfielder	Villarreal	15
	Sergio León Forward	Real Valladolid	15
	Edu Expósito Midfielder	Espanyol	15
	Nicolás Fernández Defender	Elche	15
14	Keidi Midfielder	Espanyol	14
	Barrenetxea Forward	Real Sociedad	14
	Lozano Forward	Cádiz	14
	Modric Midfielder	Real Madrid	14
	Marcos André Forward	Valencia CF	14
	En-Nesyri Forward	Sevilla	14
	Moriba Kourouma Midfielder	Valencia CF	14
	Mohamed Ali-Cho Forward	Real Sociedad	14
	Jaime Seoane Midfielder	Getafe	14
	Óscar Rodríguez Midfielder	Celta de Vigo	14
	Josep Chavarría Defender	Rayo Vallecano	14
15	Mata Forward	Getafe	13
	Juanmi Forward	Real Betis	13
	Foulquier Defender	Valencia CF	13
	Morata Forward	Atlético de Madrid	13
	Guruzeta Forward	Athletic Club	13
	Yan Couto Defender	Girona	13
	Reinier Carvalho Midfielder	Girona	13
	Marcos Alonso Defender	Barcelona	13
	Pablo Ibáñez Midfielder	Osasuna	13
	Gonzalo Villar Midfielder	Getafe	13
16	Javi Puado Forward	Espanyol	12
	Kike Barja Forward	Osasuna	12
	Negredo Forward	Cádiz	12
	Renato Tapia Midfielder	Celta de Vigo	12
	Jon Moncayola Midfielder	Osasuna	12
	Iván Sánchez Midfielder	Real Valladolid	12
	Lamela Midfielder	Sevilla	12
	Luiz Henrique Forward	Real Betis	12
	Luca De La Torre Midfielder	Celta de Vigo	12
	Alex Telles Defender	Sevilla	12
	Carles Perez Forward	Celta de Vigo	12
	Javi Hernández Defender	Girona	12
	Jorgen Strand Larsen Forward	Celta de Vigo	12
	Mojica Defender	Villarreal	12
	Lazaro Forward	Almería	12
	Toni Villa Midfielder	Girona	12
17	Álex Fernández Midfielder	Cádiz	11
	Aitor Ruibal Defender	Real Betis	11
	Lucas Vázquez Midfielder	Real Madrid	11
	Muniain Forward	Athletic Club	11
	Dani Ceballos Midfielder	Real Madrid	11
	Berenguer Forward	Athletic Club	11
	Juan Iglesias Defender	Getafe	11

LaLiga Santander

Players Player was brought on as a substitute