Patriots vs Cardinals odds and predictions: Who is the favorite for Monday Night Football?

New England Patriots vs. Arizona Cardinals live online

The New England Patriots fly to Arizona to face off against the Cardinals in an interconference contest at State Farm Stadium in Glendale, Arizona on Monday Night Football. The primetime game kicks off at 8:15 p.m. ET / 5:15 PT.

Both teams are fighting to stay in the running for a postseason berth, with the Cardinals (4-8) on the brink of elimination from the NFC playoffs, and the Patriots (6-6) hoping to halt a two-game losing streak and increase their chances at an AFC wild-card.

Odds are with the Patriots

New England is favored to prevail, winning seven of their past eight games against Arizona.

Quarterback Mac Jones is expected to play a role in the victory, as he had 22 of 36 completions for a 61.1% passing rate for 195 yards and one touchdown last week. He also had no interceptions, making it the fourth consecutive game that he hasn’t had any.

Arizona will also have to contend with New England’s defense, which is ranked one of the best in the league.

READ ALSO:

Arizona’s chances

Meanwhile, Cardinals quarterback Kyler Murray is speedy and can throw on the run. He has a 66% completion rate, throwing for 2.359 yards this season. The team can also lean on wide receiver DeAndre Hopkins, who has logged more than 80 yards in five of his six games so far, and has been an excellent possession target.

The odds indicate that it could be a tight game, with New England placed as favorites in a 2.5 point spread. Over/under is at 43.5, while the money line is set at New England -135 and Arizona at +115.