Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Defrel Forward	Sassuolo	27Player was brought on as a substitute
2	Vidal Midfielder	Internazionale	26
3	Elmas Midfielder	Napoli	25
4	Eldor Shomurodov Forward	Roma	23
5	Emanuel Vignato Forward	Bologna	21
	Sansone Forward	Bologna	21
	Lazar Samardzic Midfielder	Udinese	21
	Brandon Soppy Defender	Udinese	21
6	Gastón Pereiro Midfielder	Cagliari	20
	Alexis Forward	Internazionale	20
	Andrea Petagna Forward	Napoli	20
	Toma Basic Midfielder	Lazio	20
	Kean Forward	Juventus	20
7	Leonardo Pavoletti Forward	Cagliari	19
	Dimarco Defender	Internazionale	19
	El Shaarawy Forward	Roma	19
	Daniel Bessa Midfielder	Verona	19
	Abdoulrahmane Harroui Midfielder	Sassuolo	19
8	Ante Rebic Forward	Milan	18
	Bosko Sutalo Defender	Verona	18
9	Youssef Maleh Midfielder	Fiorentina	17
	Kevin Lasagna Forward	Verona	17
	Ignacio Pussetto Forward	Udinese	17
10	Riccardo Saponara Midfielder	Fiorentina	16
	Lucas Leiva Midfielder	Lazio	16
	Bennacer Midfielder	Milan	16
	Carles Perez Forward	Roma	16
	Jajalo Midfielder	Udinese	16
	Nadir Zortea Defender	Salernitana	16
11	Leo Stulac Midfielder	Empoli	15
	Andrea La Mantia Forward	Empoli	15
	Sofyan Amrabat Midfielder	Fiorentina	15
	Matias Vecino Midfielder	Internazionale	15
	Dejan Kulusevski Forward	Juventus	15
	Manuel Lazzari Defender	Lazio	15
	Filippo Melegoni Midfielder	Genoa	15
	Henderson Midfielder	Empoli	15
	Matheusinho Midfielder	Sassuolo	15
12	Gabriele Zappa Defender	Cagliari	14
	Callejón Forward	Fiorentina	14
	Alexis Saelemaekers Forward	Milan	14
	Adam Ounas Forward	Napoli	14
	Mertens Forward	Napoli	14
	Quagliarella Forward	Sampdoria	14
	Ansaldi Defender	Torino	14
	Don Peretz Midfielder	Venezia	14
	Tanner Tessmann Midfielder	Venezia	14
	Joaquin Correa Forward	Internazionale	14
13	Pasalic Midfielder	Atalanta	13
	Aleksa Terzić Defender	Fiorentina	13
	Cataldi Midfielder	Lazio	13
	Rade Krunic Midfielder	Milan	13
	Politano Forward	Napoli	13
	Salvador Ferrer Defender	Spezia	13
	Bonazzoli Forward	Salernitana	13
	Pandev Forward	Genoa	13
	Patrick Cutrone Forward	Empoli	13
14	Miranchuk Midfielder	Atalanta	12
	Josip Ilicic Forward	Atalanta	12
	Andreas Skov Olsen Midfielder	Bologna	12
	Nedim Bajrami Midfielder	Empoli	12
	Duncan Midfielder	Fiorentina	12
	Gagliardini Midfielder	Internazionale	12
	Bernardeschi Forward	Juventus	12
	Ibrahimovic Forward	Milan	12
	Diego Demme Midfielder	Napoli	12
	Kristoffer Askildsen Midfielder	Sampdoria	12
	Daniele Verde Forward	Spezia	12
	Domen Crnigoj Midfielder	Venezia	12
	Adrien Tameze Midfielder	Verona	12
	Caleb Ekuban Forward	Genoa	12
	Denzel Dumfries Midfielder	Internazionale	12
	Florenzi Defender	Milan	12
	Kiyine Midfielder	Venezia	12
	Keita Baldé Forward	Cagliari	12
	Junior Messias Forward	Milan	12
15	Joakim Maehle Defender	Atalanta	11
	Malinovsky Midfielder	Atalanta	11
	Filippo Bandinelli Midfielder	Empoli	11
	D'Ambrosio Defender	Internazionale	11
	Alex Sandro Defender	Juventus	11
	Ghoulam Defender	Napoli	11
	Edoardo Bove Midfielder	Roma	11
	Tommaso Augello Defender	Sampdoria	11
	Gianluca Scamacca Forward	Sassuolo	11
	M'Bala Nzola Forward	Spezia	11
	Alessandro Buongiorno Defender	Torino	11
	Hongla Midfielder	Verona	11
	Matteo Cancellieri Forward	Verona	11
	Roberto Piccoli Forward	Atalanta	11
	Giuseppe Pezzella Defender	Atalanta	11
	Hernani Midfielder	Genoa	11
	Pjaca Forward	Torino	11
	Grigoris Kastanos Midfielder	Salernitana	11
	Success Forward	Udinese	11
	Rei Manaj Forward	Spezia	11
	Kevin Agudelo Midfielder	Spezia	11
	Felix Afena-Gyan Forward	Roma	11
	Fabio Depaoli Defender	Verona	11
16	Luis Muriel Forward	Atalanta	10

Serie A

Players Player was brought on as a substitute