Athletic face Valencia as United draw Liverpool
Friday's last-16 draw threw up exciting all-Spanish and all-Premier League clashes, while Villarreal were given a tricky tie with Leverkusen and Sevilla were paired with Basel.
The draw for the Europa League last 16 took place in Nyon on Friday, with the Spanish teams in the hat experiencing mixed fortunes.
Holders Sevilla were given the most favourable tie of Spain's representatives as they were handed a clash with Swiss outfit Basel, but Villarreal are faced with a tough assignment against Bundesliga side Bayer Leverkusen.
And in one of the round's stand-out draws, Athletic Club go head to head with Gary Neville's Valencia in a mouth-watering all-La Liga encounter.
Valencia CF opponent in the last 16 in UEFA Europa League will be Athletic Club ➡ https://t.co/M6fyiD0DdY pic.twitter.com/fGGhYo0ECV
— Valencia CF (@valenciacf_en) February 26, 2016
Also dominating the round-of-16 pairings, meanwhile, is a match-up between fierce Premier League rivals Manchester United and Liverpool.
Thumbs up from Jürgen Klopp on facing @ManUtd in the @EuropaLeague! https://t.co/vMLUtVyGEX
— Liverpool FC (@LFC) February 26, 2016
The remaining Europa League last-16 ties are:
Shakhtar Donetsk-Anderlecht
Sparta Prague-Lazio
Borussia Dortmund-Tottenham Hotspur
Fenerbahçe-Braga
The first legs will be on Thursday 10 March and the returns are scheduled for seven days later, with the matches to be played at the competition's usual kick-off times of 19:00 and 21:05 CET.
The final will be held at St. Jakob-Park in Basel on 18 May.
The ties will be played on 10 and 17 March. We're in for a treat...#UELdraw pic.twitter.com/mGPl5Cthiz
— UEFA Europa League (@EuropaLeague) February 26, 2016