When is MLB Opening day 2025? Baseball’s first games of the season to kick off in Japan
Some of the key dates for the 2025 regular season have already been established. Let’s take a look.

While the Dodgers are still coming down from heady high of lifting their eighth MLB title, beating the Yankees in the 2024 World Series, the 2025 season is about to get started. Some of the key dates were already established back in the summer and what we already know is that Atlanta will host the All-Star weekend. The 95th All-Star Game will take place on Tuesday, July 15, 2025, at Truist Park, homes of the Braves.
See you in Tokyo 🇯🇵@FOXSports will air the 2025 MLB Tokyo Series featuring the @Dodgers & @Cubs pic.twitter.com/Qv1EyUctn2
— FOX Sports: MLB (@MLBONFOX) February 18, 2025
When does the 2025 MLB regular season start?
The 2025 season is just about to get underway and will take place in Japan with the Dodgers and Cubs battling it out in the Tokyo Series as part of the MLB’s World Tour.
It will be the sixth time that the new season has kicked off in the Japanese capital - on the 25th anniversary of the first-ever regular season games played in Japan in 2000 between the Cubs and the New York Mets.
The Tokyo Series will run from March 18-19 2025 with all games to be played at the Tokyo Dome, It will be the first time that four Japanese players have taken part.
One day until the 2025 season begins! #TokyoSeries pic.twitter.com/D9vYKMYVQB
— MLB (@MLB) March 17, 2025
When is Opening Day?
The Tokyo Series will be the curtain raiser for the Opening Day when all 30 teams will be in action. The 15-game slate is scheduled for March 27, 2025 - the earliest start in league history. In the 2025 regular season, each team will play six games against its prime interleague rival instead of four.
Rivalry Weekend will take place on May 16-18 with 11 of the 15 series being matchups between prime Interleague rivals. Some of those include Mets vs Yankees, Angels vs Dodgers, White Sox vs Cubs and Cardinals vs Royals, along with four non-Interleague matchups: including Pirates vs Phillies and Astros vs Rangers.
MLB's official Opening Day 2025 schedule
- Angels: March 27 at White Sox (Time TBD)
- Astros: March 27 vs. Mets (Time TBD)
- Athletics: March 27 at Mariners (10:10 p.m. ET)
- Blue Jays: March 27 vs. Orioles (3:07 p.m. ET)
- Braves: March 27 at Padres (4:10 p.m. ET)
- Brewers: March 27 at Yankees (3:05 p.m. ET)
- Cardinals: March 27 vs. Twins (4:15 p.m. ET)
- Cubs: March 18 vs. Dodgers (6:00 a.m. ET in Tokyo)
- Diamondbacks: March 27 vs. Cubs (10:10 p.m. ET)
- Dodgers: March 18 at Cubs (6:00 a.m. ET in Tokyo)
- Giants: March 27 at Reds (4:10 p.m. ET)
- Guardians: March 27 at Royals (4:10 p.m. ET)
- Mariners: March 27 vs. Athletics (10:10 p.m. ET)
- Marlins: March 27 vs. Pirates (4:10 p.m. ET)
- Mets: March 27 at Astros (Time TBD)
- Nationals: March 27 vs. Phillies (4:05 p.m. ET)
- Orioles: March 27 at Blue Jays (3:07 p.m. ET)
- Padres: March 27 vs. Braves (4:10 p.m. ET)
- Phillies: March 27 at Nationals (4:05 p.m. ET)
- Pirates: March 27 at Marlins (4:10 p.m. ET)
- Rangers: March 27 vs. Red Sox (4:05 p.m. ET)
- Rays: March 28 vs. Rockies (4:10 p.m. ET)
- Reds: March 27 vs. Giants (4:10 p.m. ET)
- Red Sox: March 27 at Rangers (4:05 p.m. ET)
- Rockies: March 28 at Rays (4:10 p.m. ET)
- Royals: March 27 vs. Guardians (4:10 p.m. ET)
- Tigers: March 27 at Dodgers (7:10 p.m. ET)
- Twins: March 27 at Cardinals (4:15 p.m. ET)
- White Sox: March 27 vs. Angels (Time TBD)
- Yankees: March 27 vs. Brewers (3:05 p.m. ET)
The 2025 regular season will be concluded on Sunday 28 September.
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