Players Player was brought on as a substitute

Pos.	Player	Team	Total
1	Gustaf Nilsson Forward	Union Saint-Gilloise	8Player was brought on as a substitute
	Edoardo Bove Midfielder	Roma	8
	Suso Midfielder	Sevilla	8
2	Jamie Leweling Forward	1. FC Union Berlin	7
	El Shaarawy Forward	Roma	7
	Cameron Puertas Midfielder	Union Saint-Gilloise	7
	Wijnaldum Midfielder	Roma	7
3	McTominay Midfielder	Manchester United	6
	Ismail Jakobs Defender	Monaco	6
	Thomas Midfielder	Arsenal	6
	Giesselmann Defender	1. FC Union Berlin	6
	Edward Chilufya Forward	FC Midtjylland	6
	Borja Iglesias Forward	Real Betis	6
	Júlio Romão Midfielder	FK Qarabag	6
	Simon Adingra Forward	Union Saint-Gilloise	6
	Désiré Doué Midfielder	Rennes	6
	Oussama El Azzouzi Midfielder	Union Saint-Gilloise	6
	F. Papoulis Forward	Omonia Nicosia	6
	Nonato Midfielder	Ludogorets Razgrad	6
	Amine Adli Forward	Bayer 04 Leverkusen	6
	Lamela Midfielder	Sevilla	6
4	Odegaard Midfielder	Arsenal	5
	Bukayo Saka Midfielder	Arsenal	5
	Patrick Walemark Forward	Feyenoord	5
	Shaw Defender	Manchester United	5
	Embolo Forward	Monaco	5
	Noah Weisshaupt Midfielder	SC Freiburg	5
	Kevin Behrens Forward	1. FC Union Berlin	5
	Beñat Turrientes Midfielder	Real Sociedad	5
	Lars Jorgen Salvesen Forward	Bodø/Glimt	5
	Anthony Olusanya Forward	HJK Helsinki	5
	Delev Forward	Ludogorets Razgrad	5
	Giorgos Naoum Midfielder	AEK Larnaka	5
	Igor Paixão Forward	Feyenoord	5
	Belotti Forward	Roma	5
	Montiel Defender	Sevilla	5
	Santiago Giménez Forward	Feyenoord	5
5	Ben White Defender	Arsenal	4
	Mads Dohr Thychosen Defender	FC Midtjylland	4
	Matteo Cancellieri Forward	Lazio	4
	Evann Guessand Forward	Nantes	4
	Canales Midfielder	Real Betis	4
	Theoson Siebatcheu Forward	1. FC Union Berlin	4
	Nicola Zalewski Midfielder	Roma	4
	Myron Boadu Forward	Monaco	4
	Danilo Forward	Feyenoord	4
	Harry Maguire Defender	Manchester United	4
	Morten Thorsby Midfielder	1. FC Union Berlin	4
	Jadon Sancho Forward	Manchester United	4
	Anthony Elanga Forward	Manchester United	4
	Alejandro Garnacho Forward	Manchester United	4
	Mats Wieffer Midfielder	Feyenoord	4
	Matias Vecino Midfielder	Lazio	4
	Coco Forward	Nantes	4
	Álex Moreno Defender	Real Betis	4
	Sven Michel Forward	1. FC Union Berlin	4
	Juninho Defender	FC Midtjylland	4
	Rashford Forward	Manchester United	4
	Dennis Appiah Defender	Nantes	4
	Adrien Truffert Defender	Rennes	4
	Leonardo Spinazzola Defender	Roma	4
	Tammy Abraham Forward	Roma	4
	Kahveci Midfielder	Fenerbahçe	4
	Jordan Teze Defender	PSV	4
	Antonio Marchesano Midfielder	Zürich	4
	Yannik Keitel Midfielder	SC Freiburg	4
	Rafael Lopes Forward	AEK Larnaka	4
	Nassim Boujellab Midfielder	HJK Helsinki	4
	Ibrahim Mustapha Forward	Crvena Zvezda	4
	Abdulkadir Omur Midfielder	Trabzonspor	4
	Djaniny Forward	Trabzonspor	4
	Avdijaj Forward	Zürich	4
	Guardado Midfielder	Real Betis	4
	Petersen Forward	SC Freiburg	4
	Emre Mor Midfielder	Fenerbahçe	4
	João Pedro Forward	Fenerbahçe	4
	Enner Valencia Forward	Fenerbahçe	4
	Álvaro Djaló Forward	Sporting Braga	4
	Ivan Ljubic Midfielder	SK Puntigamer Sturm Graz	4
	Huseynov Defender	FK Qarabag	4
	El Ghazi Forward	PSV	4
	Ezequiel Bullaude Midfielder	Feyenoord	4
	Mohamed Camara Midfielder	Roma	4
	Batshuayi Forward	Fenerbahçe	4
	Amer Gojak Midfielder	Ferencvárosi TC	4
	Azmoun Forward	Bayer 04 Leverkusen	4
	Adam Hlozek Forward	Bayer 04 Leverkusen	4
	Federico Chiesa Forward	Juventus	4
	Youssef Chermiti Forward	Sporting CP	4
	Lucas Ocampos Midfielder	Sevilla	4
6	Javairo Dilrosun Forward	Feyenoord	3
	Marcus Pedersen Defender	Feyenoord	3
	Trimmel Defender	1. FC Union Berlin	3
	Fred Midfielder	Manchester United	3
	Nikolas Dyhr Defender	FC Midtjylland	3
	Paulo Dybala Forward	Roma	3
	Lukas Kübler Defender	SC Freiburg	3
	Jantscher Forward	SK Puntigamer Sturm Graz	3
	Adam Marusic Defender	Lazio	3
	Kader Bamba Forward	Nantes	3

Europa League

Players Player was brought on as a substitute