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Cowboys-49ers odds and predictions: who is the favourite in the NFL Week 5 game?

The San Francisco 49ers are out to keep up their winning start to the season in today’s clash with the Dallas Cowboys, who head to California with a 3-1 record.

Christian McCaffrey looks set to return after injury absence
Cary EdmondsonUSA TODAY Sports via Reuters Con

A team chasing their first NFL championship since the 1994 season, the San Francisco 49ers will look to continue their 100% start to the new campaign when the Californians host the Dallas Cowboys in Week 5 today.

San Fran on streak, Dallas back to winning ways

The 49ers have scored at least 30 points per game on their to a 4-0 record so far, most recently beating the Arizona Cardinals 35-16 seven days ago.

Meanwhile, the Cowboys - who have also averaged over 30 points in 2023 - bounced back from defeat to the Cardinals in Week 3 to see off the New England Patriots 38-3 last Sunday.

Dallas, who are also chasing a first Vince Lombardi Trophy since the mid-1990s, head to Levi’s Stadium with a 3-1 record.

The 49ers and the Cowboys last met in Week 15 of the 2020 season, with Dallas prevailing 41-33 at AT&T Stadium.

Cowboys vs 49ers: betting odds

The bookmakers are backing the 49ers to clinch their first 5-0 start since 2019 - the last time they reached the Super Bowl.

Per Oddschecker, San Francisco are valued at -185 to come out on top (meaning that a $185 bet wins you $100). The Cowboys, on the other hand, are rated at +150 (a $100 bet wins you $150).

Meanwhile, the point spread is -3.5 (-110) for the 49ers and +3.5 (-110) for the Cowboys.

Cowboys vs 49ers: prediction

In his preview of the game, my colleague Andy Restrepo is predicting a 30-24 win for the 49ers. You can also check out Andy’s injury report for both teams.

Cowboys vs 49ers: when, where, how to watch?

The San Francisco 49ers host the Dallas Cowboys at Levi’s Stadium, Santa Clara, at 8:20pm ET/5:20pm PT today, Sunday 8 October 2023. TV viewers in the US will be able to watch the NFL Week 5 game on NBC.

And if you’re looking to stream the clash live online, you can do so on fuboTV, which offers users a free trial.

Video - Impressive NFL virtual reality game:

Cowboys-49ers odds and predictions: who is the favourite in the NFL Week 5 game?