Tyreek Hill becomes latest casualty on ever growing NFL 2025 season injury list

One major negative of the 2025 NFL season to date is the number of serious injuries being suffered. Only four match days have been played in the new season and already teams are seeing key players ruled out for lengthy periods or in many cases for the entire season.

Tyreek Hill is the latest high profile player to suffer after the 31-year-old after an apparent dislocated knee. The player was taken from the field as the Miami Dolphins faced the New York Jets. Early reports suggest that the wide receiver’s season is over and the Georgia native joins an ever growing list of NFL stars who face lengthy layoffs due to match sustained injuries.

Expected to miss the rest of the season

Tyreek Hill

• The Dolphins receiver suffered a dislocated left knee while making a catch in the game against the Jets and initially appears to be a season-ending injury. He was taken off the field on a stretcher and the hopes of a season return, despite not yet having an official medical report, are minimal.

Joe Burrow

• The Bengals quarterback suffered a severe turf toe injury (grade 3) to his left foot during the second week of the season, requiring surgery shortly after. His recovery is estimated to take at least three months, which would keep him out of action for much of the regular season.

Malik Nabers

• The Giants receiver suffered a torn anterior cruciate ligament (ACL) in his right knee against the Chargers after an awkward fall while extending on a deep pass and has been was ruled out for the season.

Najee Harris

• The Chargers running back was placed on injured reserve after suffering a ruptured Achilles tendon in his left leg. The injury, resulting from a non-contact movement, keeps him out for the remainder of the season.

Nick Bosa

• The 49ers defensive end concluded his season after a torn anterior cruciate ligament in his right knee was revealed. The injury occurred during a game against the Cardinals, and the club confirmed he will undergo surgery to recover.

James Conner

• James Conner suffered a serious right ankle injury that will require surgery. The Cardinals confirmed that his season is over and that they would place him on the injured reserve list to free up roster space.

Nnamdi Madubuike

• The Ravens defensive tackle suffered a neck injury in (Week 2 against the Cleveland Browns), which has resulted in him not being able to finish the 2025 season.

Hoping to make a return soon

Joe Mixon

• The Houston Texans’ new running back injured his ankle during the preseason. He has not returned yet, but is expected to do so within the next three weeks.

Khalil Mack

• Chargers linebacker Khalil Mack was placed on injured reserve with an elbow injury this season and is expected to make a return in the next few weeks although a definitive expected return date has not yet been communicated.

CeeDee Lamb

• Lamb has been hampered by a sprained ankle suffered against the Bears, which will prevent him from participating in upcoming games.

Mike Evans

• The veteran Tampa Bay receiver injured his hamstring during a game against the Jets. Medical estimates indicate he could miss two to four weeks, depending on his progress and the severity of the sprain.

Lamar Jackson

• Baltimore’s star quarterback is also facing a setback. He strained his hamstring during Week 4’s game against the Kansas City Chiefs, forcing him to leave the game in the third quarter. The exact extent of the damage is still being determined, and his status for the upcoming games is uncertain.

George Kittle

• The San Francisco tight end suffered a hamstring injury during the season-opening game against the Seahawks, forcing him to leave the field in the second quarter. The 49ers have placed him on injured reserve, with the expectation that he could return for Week 6.

Aaron Jones

• The Vikings running back was placed on the injured list (IR) after suffering a hamstring injury during the home loss to the Falcons. The injury will keep him out until at least Week 7.

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