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Who won Sunday Night Football in NFL Week 5?

The Arizona Cardinals continued their unblemished start to the NFL season on Sunday, but the Jacksonville Jaguars' losing run went on.

GLENDALE, ARIZONA - OCTOBER 10: Chandler Jones #55 of the Arizona Cardinals celebrates after defeating the San Francisco 49ers 17-10 at State Farm Stadium on October 10, 2021 in Glendale, Arizona.   Christian Petersen/Getty Images/AFP
Christian PetersenAFP

The Arizona Cardinals extended their perfect start to the NFL season on Sunday, while the Jacksonville Jaguars closed in on an unwanted record after losing again in Week 5.

Cardinals make it five wins out of five

The Cardinals, the league’s only remaining unbeaten team, moved to 5-0 after earning a 17-10 victory over the San Francisco 49ers, for whom rookie quarterback Trey Lance made his first start in the absence of the injured Jimmy Garoppolo.

Chargers move to 4-1, Cowboys down Giants

In Los Angeles, the Chargers also continued their good start to the season, going to 4-1 as they were led by QB Justin Herbert to an entertaining 47-42 win over the Cleveland Browns (3-2), who had been 27-13 ahead at the start of the second half.

In Dallas, the Cowboys comprehensively saw off the injury-hit New York Giants, who lost key men Daniel Jones and Saquon Barkley to an ankle problem and concussion, respectively. Dak Prescott threw for three touchdowns as the Cowboys (4-1) earned a fourth straight triumph, running out 44-20 winners. The defeat leaves the Giants at 1-4.

Brady injured in Bucs' win over Dolphins

Fresh from surpassing Drew Brees’ career passing yards record, superstar quarterback Tom Brady threw for five TDs as the Tampa Bay Buccaneers improved to 4-1 with a 45-17 win over the Miami Dolphins (1-4), but is doubtful for Week 6 after hurting his hand.

Speaking post-match, Brady was non-committal over his playing status for Thursday’s matchup with the Philadelphia Eagles, telling reporters: "I mean it's just a kind of a football injury. So, do my best you know to get ready for this game. We'll see what happens."

Jaguars lose yet again

The Kansas City Chiefs, the team beaten by the Bucs in Super Bowl LV in February, went down 38-20 to the 4-1 Buffalo Bills and are now 2-3 amid an indifferent start to the season, while the Jacksonville Jaguars’ 37-19 defeat to the Tennessee Titans means they are 0-5 and have lost their last 20 NFL games.

The Jaguars are now moving dangerously close to equalling the 26-game NFL-record losing streak endured by the Bucs between 1976 and 1977.

NFL back in London as Falcons beat Jets

At London’s Tottenham Hotspur Stadium, meanwhile, the NFL returned to the UK for the first time in two years as the Atlanta Falcons moved to 2-3 with a 27-20 victory over the New York Jets (1-4).

All Week 5's Sunday Night Football results

Jets 20-27 Falcons

Lions 17-19 Vikings

Saints 33-22 Washington

Patriots 25-22 Texans

Dolphins 17-45 Buccaneers

Packers 25-22 Bengals

Broncos 19-27 Steelers

Eagles 21-18 Panthers

Titans 37-19 Jaguars

Browns 42-47 Chargers

Bears 20-9 Raiders

49ers 10-17 Cardinas

Giants 20-44 Cowboys

Bills 38-20 Chiefs